Symbol
Name
ID

Fgfr2
fibroblast growth factor receptor 2
MGI:95523

Phenotype annotations related to respiratory system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Respiratory distress	Bronchomalacia	Anomalous tracheal cartilage	Tracheal cartilaginous sleeve	Upper airway obstruction
Disease(s) Associated with FGFR2	Respiratory distress	Bronchomalacia	Anomalous tracheal cartilage	Tracheal cartilaginous sleeve	Upper airway obstruction
acrocephalosyndactylia
Antley-Bixler syndrome without disordered steroidogenesis
Beare-Stevenson cutis gyrata syndrome
Pfeiffer syndrome

Mouse Phenotypes

respiratory system phenotype

abnormal pulmonary circulation

abnormal nasal bone morphology

short nasal bone

abnormal nasal capsule morphology

abnormal nasal septum cartilage morphology

abnormal nasal gland morphology

abnormal lateral nasal gland morphology

thick nasal septum

pulmonary alveolar proteinosis

bronchiolectasis

abnormal lung morphology

abnormal lung development

impaired branching involved in bronchus morphogenesis

impaired branching involved in trachea morphogenesis

impaired lung alveolus development

impaired lung lobe morphogenesis

small lung

pulmonary hypoplasia

abnormal pulmonary acinus morphology

atelectasis

abnormal bronchiole morphology

abnormal right lung morphology

absent lungs

abnormal tracheal cartilage morphology

fused tracheal cartilage rings

abnormal respiration

respiratory distress

respiratory failure

Availability

Mouse Genotype

Fgfr2^hob/Fgfr2^hob

Fgfr2^m1Sgg/Fgfr2^m1Sgg

Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn

Fgfr2^tm1Schl/Fgfr2^tm1Schl

Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni

Fgfr2^tm2Schl/Fgfr2^tm2Schl

Fgfr2^tm3Dsn/Fgfr2^tm3Dsn

Fgfr2^tm4Lni/Fgfr2^tm4Lni

Fgfr2^m1Sgg/Fgfr2⁺

Fgfr2^tm1.1Dor/Fgfr2^hob

Fgfr2^tm2.3Dsn/Fgfr2⁺

Fgfr2^tm3.1Cxd/Fgfr2⁺

Fgfr2^tm1Dor/Fgfr2^tm1Dor
Tg(Sftpc-cre)1Blh/0 (conditional)

Fgfr2^tm1Ewj/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm2Cxd/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm2Ewj/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm3Cxd/Fgfr2⁺
Tg(Col2a1-cre)1Xya/0 (conditional)

Fgfr2^tm3Cxd/Fgfr2⁺
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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